ABSTRACT
Objective:To observe whether the effect of electroacupuncture (EA) on improving sex hormone disorders and follicle development is by decreasing the expression of anti-Mullerian hormone (AMH) in rats with experimental polycystic ovarian syndrome (PCOS).Methods:Forty rats were randomly divided into four groups,a normal group (NG),a model group (MG),an EA at acupoints group (EAAG),and an EA at non-acupoints group (EANAG),with 10 rats in each group.The rats in the EAAG and EANAG were intervened by EA treatment for consecutive 14 d.Zhongji (CV 3) and Guanyuan (CV 4) were selected as the acupoints in the EAAG,and the tip of the tail and 1 cm up from the tail tip were selected as the non-acupoints in the EANAG.After treatment,the histomorphological changes of the ovary,the levels of aromatase P450 (P450arom),testosterone and estradiol in the ovarian tissues,and the expressions of follicle stimulating hormone (FSH) and AMH were observed.Results:After treatment,compared with the MG and EANAG,the expression of AMH decreased (P＜0.05),the levels of P450arom and estradiol increased significantly,and the level of testosterone decreased significantly (all P＜0.01) in the EAAG.Additionally,several normal follicles were present and the number of cystically dilated follicles decreased in the EAAG.Compared with the MG and EANAG,the EAAG obviously had more follicular granulosa cells.Conclusion:EA can down-regulate the abnormally increased expression of AMH to improve sex hormone disorders and follicle development in PCOS rats.
ABSTRACT
<p><b>OBJECTIVE</b>To discuss the therapeutic effects of electroacupuncture on benign prostatic hyperplasia and the impacts on hormone levels in the patients.</p><p><b>METHODS</b>Sixty patients were randomized into an electroacupuncture group and a medication group, 30 cases in each one. In the electroacupuncture group, electroacupuncture was applied to Zhongji (CV 3) and Qugu (CV 2), once a day, 5 times a week. In the medication group, tamsulosin hydrochloride sustained-release capsules were prescribed for oral administration, 0.2 mg, once a day. The duration of treatment was 6 weeks in both of the two groups. The changes in serum testosterone (T), estradiol (E) and E/T, the international prostate symptom score (IPSS) and its erectile function score (ⅡEF5) and serum prostate specific antigen (PSA) as well as the adverse reactions were observed before and after treatment in the two groups. The clinical therapeutic effects were compared between the two groups.</p><p><b>RESULTS</b>Before and after treatment, the differences in serum T, Eand E/T were not significant in the electroacupuncture group (all>0.05); the difference in E/T was significant in the medication group (<0.05). The differences in serum T, Eand E/T were not significant between the two groups (all>0.05). IPSS was reduced as compared with that before treatment in the electroacupuncture group (<0.05) and was not different significantly as compared with that before treatment in the medication group (>0.05). The difference was significant in comparison of the two groups after treatment (<0.05), and the electroacupuncture group was better. After treatment, the symptom severity was reduced apparently in the electroacupuncture group and the overall situation was better than that in the medication group (<0.05). ⅡEF5 score and PSA were not different significantly before and after treatment in the two groups and between the two groups (all>0.05). The total effective rate was 60.7% (17/28) in the electroacupuncture group, apparently better than 30.8% (8/26,<0.05) in the the medication group.</p><p><b>CONCLUSIONS</b>Electroacupucnture at Zhongji (CV 3) and Qugu (CV 2) apparently relieves the symptoms in the patients and the therapeutic effects are better than the oral administration of tamsulosin hydrochloride sustained-release capsules, but electroacupuncture has not apparent impacts on serum T and Elevels.</p>
ABSTRACT
Objective:To observe the effect of postoperative urinary retention treated with tuina therapy.Methods:Tuina therapy was applied on 37 cases of postoperative urinary retention;Qihai(CV 6),Guanyuan(CV 4),Zhongji(CV 3)and bilateral Sanyinjiao(SP 6)were selected.Results:Thirty-six cases were cured and 1 case was not surveyed after 1 to 3 treatments.Conclusion:Point tuina is an effective method in treating postoperative urinary retention.